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In the concanavalin A (ConA)-induced autoimmune hepatitis model, pretreatment with RvD1 or RvE1 markedly reduced the release of TNF-α, IFN-γ, IL-2, IL-1β, and IL-6, while simultaneously suppressing CD4⁺ and CD8⁺ T-cell infiltration through the inhibition of NF-κB and AP-1 signaling [244]
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