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IGF1R Nuclear Localization in Glioma Cells Shortens Tumor Latency and Contributes to Tumor Growth To study the effect of IGF1R subcellular localization in vivo , using subcutaneous xenografts as a proof of concept, 1.5 × 10 6 U87Empty, U87WT, or U87Mut cells were injected subcutaneously in immunodeficient male mice [N:NIH (S)- Fox 1 nu ]

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