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10.1016/s0140-6736(23)00966-2 [DOI] [PubMed] [Google Scholar] Li H

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101 Extravasation of leukocytes is achieved by three fundamental processes: Adhesion —of integrin to VCAM and ICAM, which are overexpressed in response to stress cytokines secreted by glial cells Extravasation —adhesion signals a conformational change in the actin cytoskeleton, which creates a window in the BBB for extravasation of cells