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To circumvent this issue, researchers explored the possibility of generating ECM to be decellularized by in vitro culturing the needed cells [188]

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Notably, interleukin-5 (IL-5) is the primary eosinophil growth and survival factor, and eotaxin-1 (CCL11) is a key chemokine attracting eosinophils to gut tissue ( 76 – 78 )