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Ageing Res Rev (2006) 5(3):310–31

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The earliest controlled human evidence for luteolin’s neuroimmune effects comes from a randomized, double-blind clinical trial that evaluated a complex of PEA-LUT in children with autism spectrum disorder ( A recent double-blind, placebo-controlled crossover trial evaluated the effects of luteolin supplementation (250 mg taken twice daily for 2 weeks) on neurocognitive performance in healthy adults

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