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[3] It is typically prescribed for people who cannot absorb biotin from food or supplements normally (for example, those with certain metabolic disorders or individuals on long-term intravenous feeding)

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Briefly, the DAPI staining was used to create a nuclear mask, and fluorescence intensities of the stained markers (FOXO4, CDKN2A, CDKN1A, and TP53) and FOXO4 foci were measured within the nuclear mask