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Notably, while it is clear that PVAT mass is increased in animal models and humans with obesity [40], the impact of sex on this increase is less clear

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Given the indispensability of NEM or other alkylating agents such as iodoacetamide (IAA) for the accurate analysis of GSH, the majority of recently reported and validated LC-MS-based methods measure the GSH-NEM or GSH-IAA thioethers in parallel with native GSSG (Scheme 3)