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12, 13, 14 Together, the pathological features of T2D—notably elevated serum concentrations of inflammatory cytokines, glucose, insulin and free insulin-like growth factor-1 (IGF-1)—provide a pro-tumorigenic environment that may account for the increased risk of diabetic and obese patients for the development of cancer at various sites 11 as well as the worse prognosis of patients with cancer that display one or more of these abnormalities

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Wiraguna et al studied serum glutathione levels and tried to correlate them with melasma area severity index score (MASI)

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