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Cells were cultured in Dulbecco’s Modified Eagle’s Medium (DMEM) supplemented with 10% fetal bovine serum, 2 mM L-glutamine and 100 U/mL penicillin/streptomycin (all from WelGENE Inc., Daegu, Republic of Korea) at 37 °C in a humidified 5% CO 2 atmosphere