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Phase 3 TRANSCEND-T2D-1 Trial (March 2026, topline data): In 537 adults with inadequately controlled type 2 diabetes (HbA1c 7.0-9.5%), retatrutide produced HbA1c reductions of -1.7% to -2.0% (vs -0.8% placebo) and weight loss of 11.5% to 16.8% over 40 weeks