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These agents can also regulate hyperactivity of the HPA axis, enhance neuroplasticity and BDNF expression, mitigate neuroinflammation and oxidative stress, and safeguard mitochondrial function, thus improving cellular bioenergetics

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Thioesterase assays ABHD11 reconstitution assay A total of 1 × 10 6 HeLa cells treated with or without 2.5 µM ML226 for 6 h were lysed and immunoprecipitated as described