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Introduction All living cells have extracellular polysaccharide structures attached

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Within the hepatic environment, TMA is subjected to oxidation by flavin-containing monooxygenases (FMO), resulting in the conversion of TMA to TMAO, the fully oxidized derivative of the compound ( Figure 2 One mechanism by which the body maintains TMAO homeostasis is through excretion, the kidney is the prominent organ to eliminate TMAO