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We can divide the autonomic nervous system into categories: the sympathetic system (stress response), the parasympathetic system (rest response), and the enteric nervous system (digestive system).[ref] Small nerve fibers control the following systems: heart rate variability with deep respiration (e.g., Valsalva maneuver) heart rate and blood pressure response to postural change (e.g., standing up after lying down) urine flow rate and feeling of need to urinate isometric exercise sweating skin wrinkling in water Thus, damage to the small nerve fibers can cause disruption in heart rate, blood pressure, bladder irritation, lack of sweating, and a lack of skin wrinkling when in water for 30 minutes.[ref][ref] How do nerves fire

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J Biol Chem 253:4305–4309 [PubMed] [Google Scholar] 152.Wingrove J, Makaronidis J, Prados F, Kanber B, Yiannakas MC, Magee C, Castellazzi G, Grandjean L, Golay X, Tur C, Ciccarelli O, D’Angelo E, Gandini Wheeler-Kingshott CAM, Batterham RL (2023) Aberrant olfactory network functional connectivity in people with olfactory dysfunction following Covid-19 infection: an exploratory, observational study