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Disulfiram, a drug clinically used in the treatment of chronic alcoholism, has been found to have anti-cancer activity [139,140]

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However, at very HA, impaired cerebral dynamic in blood flow [48], reduced cerebral glucose metabolism [49], reduced cerebral vascular reactivity [50,51], altered gray and white matter [42], and altered neuronal activity are some of the alterations that may affect neurocognitive functioning [52]