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Significantly, the prevalence of sarcopenia is approximately 10%–50% in people aged ≥ 60 years, which has become a serious challenge for global health (Witham and Aihie Sayer, 2016)

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Iron chelators delivered using nanoparticles have been observed to cross the blood–brain barrier (BBB) to deliver the drug to the brain while also effectively preventing metal-associated oxidative damage