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Biomonitoring equivalents for toxic concentrations of Se in a variety of body fluids have been calibrated using various regulatory limits set by the Institute of Medicine (upper limits), USEPA (reference dose) and ATSDR chronic (minimum risk level) and were established using Chinese cohort data to define guideline levels to protect against selenosis (Reference Hays, Macey and Nong46)

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Vitamin C exhibited less protection, with approximately 40% of hepatocytes displaying vacuolation at 40x magnification and enlarged and other normal hepatocytes (fig

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